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Updated: May 3, 2026

An Efficient and Simple Method to Establish NK and T Cell Lines from Patients with Chronic Active Epstein-Barr Virus Infection
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An Efficient and Simple Method to Establish NK and T Cell Lines from Patients with Chronic Active Epstein-Barr Virus Infection

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Epstein-barr virus-induced hemophagocytic lymphohistiocytosis

K Goudarzipour1, M Kajiyazdi1, A Mahdaviyani2

  • 1Mofid, Children's Hospital, shahid beheshti University of Medical Sciences, Tehran, Iran.

International Journal of Hematology-Oncology and Stem Cell Research
|February 8, 2014
PubMed

Hemophagocytic lymphohistiocytosis (HLH) is one of the complications of Epstein-Barr virus (EBV) infection. Although the patients who have developed HLH following EBV have normal immune system, there are a few patients with EBV-induced immune deficiency who develop HLH as well. Here, we describe the case of a 10-year-old girl with neurological complications caused by EBV-induced HLH. The patient received rituximab, leading to weakening inflammation associated with EBV infection and suppression of disease through quick treatment.

Keywords:
Epstein - Barr virusEtanerceptHemophagocytic lymphohistiocytosisInfectious mononucleosisSystemic inflammatory response syndromeX-Linked lymphoproliferative disease

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