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Updated: May 3, 2026

Dual Effects of Melanoma Cell-derived Factors on Bone Marrow Adipocytes Differentiation
Published on: August 23, 2018
Adiponectin and leptin molecular actions and clinical significance in breast cancer
Mohan Reddy Nalabolu1, Kalyani Palasamudram1, Kaiser Jamil1
1Research Scholar, Bhagwan Mahavir Medical Research Center, Department of Genetics, Mahavir Marg, A.C.Guards, Hyderabad-500004, Andhra Pradesh, India.
Abstract:
Obesity is an important public health problem and major risk factor for postmenopausal breast cancer. Adipose tissue is the major component involved in the control of the metabolism through energy homeostasis, adipocyte differentiation, insulin sensitivity and the activation of anti-inflammatory metabolic and immune pathways. Leptin and Adiponectin pathways are involved in proliferation process in breast cancer. Current review describes potential relationship between the molecular actions and clinical significance of leptin and adiponectin in breast cancer.
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