[Function of the histamine-histaminase system in the dynamics of experimental acute pancreatitis]

The action of histamine-histaminase in progressing pancreatitis has been studied in conformity with neurohumoral theory of pancreatitis pathogenesis. Phase modifications have been revealed. Violation of the relations arising in the system during the first 24 hours of the disease is brought to normal in the subsequent period of pathological process. The study of the system makes it possible to agree with the recommendation of the use of antihistamine preparations in the clinical practice.