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Related Experiment Video

Updated: May 3, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
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Late prematurity: a systematic review.

Luís Carlos Machado Júnior1, Renato Passini Júnior1, Izilda Rodrigues Machado Rosa2

  • 1Department of Obstetrics and Gynecology, Faculdade de Ciências Médicas, Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazil.

Jornal De Pediatria
|February 11, 2014
PubMed
Summary
This summary is machine-generated.

Late preterm births, occurring between 34 and 36 weeks, are increasing and linked to higher mortality and long-term health issues. Strategies to improve outcomes for these infants are being evaluated.

Keywords:
Early neonatal mortalityGravidez de alto riscoHigh-risk pregnancyInfant mortalityMortalidade infantilMortalidade neonatalMortalidade neonatal precoceNeonatal mortalityPreterm laborTrabalho de parto prematuro

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Area of Science:

  • Perinatal Medicine
  • Neonatology
  • Public Health

Background:

  • Late preterm birth (34 to 36 weeks and 6 days gestation) represents a growing proportion of preterm births.
  • This demographic is associated with increased risks compared to full-term infants.

Purpose of the Study:

  • To conduct a comprehensive literature review on late preterm births.
  • To examine various aspects including incidence, outcomes, and potential interventions.

Main Methods:

  • Systematic search of MEDLINE, LILACS, and Cochrane Library databases.
  • Inclusion of references from retrieved articles without time limitations.

Main Results:

  • Late preterm births show a recent increase and constitute the majority of preterm births.
  • Strong associations found with neonatal mortality, childhood mortality, and young adult mortality.
  • Linked to numerous neonatal complications and long-term sequelae such as cerebral palsy, asthma, and diabetes.

Conclusions:

  • Late preterm infants face significantly higher mortality and morbidity, along with long-term developmental challenges.
  • Emerging strategies focus on antenatal corticosteroids and modified delivery/neonatal care guidelines.
  • Further research is essential to validate and refine these interventions for improved neonatal outcomes.