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[Intravitreal bevacizumab for choroidal neovascularization associated with Best's disease]
D Velazquez-Villoria1, C Macià Badia1, J Rigo Quera1
1Servicio de Oftalmología, Hospital Vall d'Hebrón, Barcelona, España.
Archivos De La Sociedad Espanola De Oftalmologia
|February 11, 2014
Summary
A single intravitreal injection of bevacizumab effectively treated choroidal neovascularization in a patient with Best's disease, restoring vision. This treatment showed sustained visual acuity over a 12-month follow-up period.
Area of Science:
- Ophthalmology
- Medical Genetics
Background:
- Best's disease is a rare inherited retinal disorder.
- Choroidal neovascularization (CNV) is a common complication leading to vision loss.
Observation:
- A 27-year-old woman presented with vision loss (20/200) in her right eye.
- Ophthalmoscopy revealed macular hemorrhage and neurosensory detachment; the left eye showed vitelliform deposits.
- Diagnostic tests confirmed CNV associated with Best's disease.
Findings:
- A single intravitreal injection of bevacizumab was administered.
- Visual acuity improved to 20/25 within four weeks.
- Visual acuity remained stable during a 12-month follow-up.
Implications:
- Intravitreal bevacizumab is a promising treatment for CNV in Best's disease.
- This approach may help preserve or restore vision in affected individuals.
- Further research is warranted to confirm long-term efficacy and safety.
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