Related Experiment Video
Updated: Sep 30, 2026
Fluorescence-activated Cell Sorting for Purification of Plasmacytoid Dendritic Cells from the Mouse Bone Marrow
Published on: November 4, 2016
Unusual "cytokine" activities of the random polymer (Glu60, Phe40) in murine immune systems
P H Maurer1, D C Liu, J L Grun
1Thomas Jefferson University, Philadelphia, PA 19107.
When the random polymer (Glu, Phe)n was added to primary lymph node T cell cultures from mice immunized with (Glu, Lys, Ala) and other immunogens, significant inhibition of [3H]thymidine incorporation was noted. A similar addition of (Glu, Phe)n to murine T cell lines (Fathman) from the above reacting lymph nodes led to augmentation of maximal incorporation of [3H]thymidine. The importance of the antigen presenting cells in these phenomena and the possible role of IL-1 in these observations will be documented.
When the random polymer (Glu, Phe)n was added to primary lymph node T cell cultures from mice immunized with (Glu, Lys, Ala) and other immunogens, significant inhibition of [3H]thymidine incorporation was noted. A similar addition of (Glu, Phe)n to murine T cell lines (Fathman) from the above reacting lymph nodes led to augmentation of maximal incorporation of [3H]thymidine. The importance of the antigen presenting cells in these phenomena and the possible role of IL-1 in these observations will be documented.
More Related Videos
11:48Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes
Published on: May 31, 2018
09:05Generation of Large Numbers of Myeloid Progenitors and Dendritic Cell Precursors from Murine Bone Marrow Using a Novel Cell Sorting Strategy
Published on: August 10, 2018