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Cesarean delivery and risk of childhood obesity
Zhengcun Pei1, Joachim Heinrich2, Elaine Fuertes3
1Institute of Epidemiology I, German Research Center for Environmental Health, Neuherberg, Germany; Faculty of Medicine, Ludwig Maximilian University of Munich, Munich, Germany.
Insights
Cesarean delivery may increase the risk of childhood obesity in early years. However, this study did not find evidence linking cesarean birth to obesity in later childhood.
Area of Science:
- Pediatric Health
- Obstetrics
- Public Health
Background:
- Childhood obesity is a growing public health concern.
- Cesarean delivery rates have increased globally.
- Understanding risk factors for childhood obesity is crucial.
Purpose of the Study:
- To determine if cesarean delivery is a risk factor for childhood obesity.
- To investigate the association between birth mode and obesity at different childhood ages.
Main Methods:
- Prospective cohort study of healthy, full-term infants.
- Obesity defined by World Health Organization (WHO) growth standards.
- Multivariate logistic regression adjusted for confounders.
Main Results:
- Cesarean delivery was associated with a higher likelihood of obesity at age 2 years (aOR 1.68).
- No significant association was found for obesity at ages 6 or 10 years.
- Mothers with cesarean births had higher pre-pregnancy BMI and gestational weight gain.
Conclusions:
- Cesarean delivery may be a risk factor for early childhood obesity.
- The study does not support a link between cesarean delivery and later childhood obesity.
- Further research is needed to elucidate the mechanisms involved.
Objective:
To investigate whether birth by cesarean delivery rather than vaginal delivery is a risk factor for later childhood obesity.
Study Design:
Healthy, full-term infants were recruited. Overweight and obesity were defined using measured weight and height according to World Health Organization reference data. Associations between cesarean delivery and being overweight or obese were investigated at age 2, 6, and 10 years (n = 1734, 1244, and 1170, respectively) by multivariate logistic regression models adjusted for socioeconomic status, child characteristics, and maternal prepregnancy characteristics.
Results:
Mothers who gave birth by cesarean delivery (∼17%) had a higher mean prepregnancy body mass index (23.7 kg/m(2) vs 22.5 kg/m(2)), greater mean gestational weight gain (15.3 kg vs 14.5 kg), and shorter mean duration of exclusive breastfeeding (3.4 months vs 3.8 months) compared with those who delivered vaginally. The proportion of obese children was greater in the cesarean delivery group compared with the vaginal delivery group at age 2 years (13.6% vs 8.3%), but not at older ages. Regression analyses revealed a greater likelihood of obesity at age 2 years in the cesarean delivery group compared with the vaginal delivery group at age 2 years (aOR, 1.68; 95% CI, 1.10-2.58), but not at age 6 years (aOR, 1.49; 95% CI, 0.55-4.05) or age 10 years (aOR, 1.16; 95% CI, 0.59-2.29).
Conclusion:
Cesarean delivery may increase the risk of obesity in early childhood. Our results do not support the hypothesis that an increasing rate of cesarean delivery contributes to obesity in childhood.
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