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Updated: May 3, 2026

Induction and Monitoring of Active Delayed Type Hypersensitivity DTH in Rats
Published on: July 19, 2007
Delayed hypersensitivity reaction after initial dose of infliximab: a case report
Anna Krajcovicova1, Tibor Hlavaty, Zuzana Zelinkova
1Gastroenterology Unit, Department of Internal Medicine V., University Hospital Bratislava, Bratislava, Slovakia.
Abstract:
We report here an unusual case of delayed hypersensitivity reaction in a young woman with ulcerative colitis after the first administration of infliximab (IFX). The patient developed severe serum-sickness-like reaction, and her anti-IFX antibody titer increased rapidly after a single infusion of IFX. The possible reason for the delayed hypersensitivity reaction to a single IFX exposure might be the presensitization of the patient by murine antigens as she had been keeping mice and hamsters as pets for several years.
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