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A case report and literature overview: Abiotrophia defectiva aortic valve endocarditis in developing countries
J N Ramos1, L S dos Santos, L M R Vidal
1Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro (FCM/UERJ), Rio de Janeiro, RJ, Brazil.
A fatal case of aortic valve endocarditis caused by Abiotrophia defectiva was documented in Brazil. This study also reviewed other human infections linked to Abiotrophia defectiva in developing nations.
Area of Science:
- Infectious Diseases
- Cardiology
- Microbiology
Background:
- Endocarditis is a serious infection of the heart lining or valves.
- Abiotrophia defectiva is a gram-positive bacterium, part of the normal human flora, but can cause opportunistic infections.
Observation:
- A fatal case of aortic valve endocarditis in Brazil was attributed to Abiotrophia defectiva.
- The patient's presentation and diagnostic findings were detailed.
Findings:
- This report highlights a rare but severe manifestation of Abiotrophia defectiva infection.
- A review of similar cases in developing countries was conducted to understand the epidemiology and clinical spectrum.
Implications:
- Increased awareness of Abiotrophia defectiva as a potential pathogen in endocarditis, particularly in resource-limited settings.
- Highlights the need for appropriate diagnostic and treatment strategies for infections caused by nutritionally variant streptococci (NVS) like Abiotrophia defectiva.
Related Concept Videos
Endocarditis I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis III: Medical Management
Aortic Regurgitation I: Introduction
Rheumatic Heart Disease I: Introduction
Aortic Regurgitation II: Clinical Features and Diagnostic Tests

