Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

7.0K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
7.0K
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

1.4K
1.4K
Tumor Immunotherapy01:27

Tumor Immunotherapy

2.5K
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
2.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Systemic viral vector vaccination induces brain resident memory T cells to drive anti-glioblastoma immunity.

bioRxiv : the preprint server for biology·2026
Same author

AI and algorithmic literacy among health workers: a scoping review through a digital health literacy lens.

Frontiers in public health·2026
Same author

Managing Suicidality: The Experiences of Canadian-Based Racialized Gay, Bisexual, Transgender, and Queer (GBTQ) Men.

Qualitative health research·2026
Same author

Health Equity Analysis of Awareness and Use of GetCheckedOnline, British Columbia's Digital Intervention for Sexually Transmitted and Blood-Borne Infection Testing in 5 Urban, Suburban, and Rural Communities: Cross-Sectional Survey Study.

Journal of medical Internet research·2026
Same author

Acceptability of HIV self-testing among sexual health service providers and Two-Spirit, gay, bisexual, and queer men in Ontario, Canada.

Health promotion international·2026
Same author

Trends in the Incidence of HPV-Associated Anal Cancer by Risk Group, 1990-2019: A Population-Based Cohort Study in British Columbia, Canada.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology·2026

Related Experiment Video

Updated: May 3, 2026

Author Spotlight: Innovative Cancer Therapies with Iron Oxide Nanoparticles for Glioblastoma Treatment
09:02

Author Spotlight: Innovative Cancer Therapies with Iron Oxide Nanoparticles for Glioblastoma Treatment

Published on: September 27, 2024

2.2K

Targeted therapy in gliomas.

Mohamed Ali Hamza1, Mark Gilbert

  • 1The University of Texas MD Anderson Cancer Center, Houston, TX, USA, m_hamza67@hotmail.com.

Current Oncology Reports
|February 11, 2014
PubMed
Summary
This summary is machine-generated.

Despite treatment advances, malignant glioma survival remains poor due to tumor heterogeneity. This review highlights molecular targets and clinical trial outcomes for targeted glioma therapies, aiming to improve patient survival.

More Related Videos

Preparation Of Neovascular Tissues from Human Glioma Tissues for Quantitative Proteomics Analysis of Tumor Angiogenesis
09:33

Preparation Of Neovascular Tissues from Human Glioma Tissues for Quantitative Proteomics Analysis of Tumor Angiogenesis

Published on: March 20, 2026

120
Generation of CAR T Cells for Adoptive Therapy in the Context of Glioblastoma Standard of Care
12:55

Generation of CAR T Cells for Adoptive Therapy in the Context of Glioblastoma Standard of Care

Published on: February 16, 2015

19.9K

Related Experiment Videos

Last Updated: May 3, 2026

Author Spotlight: Innovative Cancer Therapies with Iron Oxide Nanoparticles for Glioblastoma Treatment
09:02

Author Spotlight: Innovative Cancer Therapies with Iron Oxide Nanoparticles for Glioblastoma Treatment

Published on: September 27, 2024

2.2K
Preparation Of Neovascular Tissues from Human Glioma Tissues for Quantitative Proteomics Analysis of Tumor Angiogenesis
09:33

Preparation Of Neovascular Tissues from Human Glioma Tissues for Quantitative Proteomics Analysis of Tumor Angiogenesis

Published on: March 20, 2026

120
Generation of CAR T Cells for Adoptive Therapy in the Context of Glioblastoma Standard of Care
12:55

Generation of CAR T Cells for Adoptive Therapy in the Context of Glioblastoma Standard of Care

Published on: February 16, 2015

19.9K

Area of Science:

  • Neuro-oncology
  • Molecular biology
  • Clinical pharmacology

Background:

  • Malignant gliomas have poor survival outcomes despite current multimodal treatments.
  • Tumor molecular heterogeneity drives treatment resistance in gliomas.
  • Advances in understanding glioma pathogenesis have identified novel therapeutic targets.

Purpose of the Study:

  • To review key molecular targets for glioma therapy.
  • To summarize clinical trial outcomes for targeted agents in glioma patients.
  • To assess the potential of targeted therapies to improve survival.

Main Methods:

  • Literature search of published clinical trials.
  • Review of studies on molecular targets in glioma.
  • Synthesis of data on targeted therapeutic agents and patient outcomes.

Main Results:

  • Several molecular targets have been identified in glioma.
  • Clinical trials of targeted agents show varying efficacy.
  • Targeted therapies offer potential for improved glioma treatment.

Conclusions:

  • Targeted molecular therapies represent a promising strategy for malignant gliomas.
  • Further research and clinical trials are needed to optimize targeted treatment approaches.
  • Personalized medicine based on molecular profiling may enhance glioma patient outcomes.