Patient-reported health as a prognostic factor for adverse events following percutaneous coronary intervention

Area of Science:

• Cardiovascular Medicine
• Health Outcomes Research
• Patient-Reported Outcomes

Background:

• Previous research on self-reported health and coronary heart disease (CHD) outcomes may be affected by selection bias.
• Understanding the link between patient-perceived health and adverse events after percutaneous coronary intervention (PCI) is crucial for improving patient care.

Purpose of the Study:

• To investigate the association between self-rated health and adverse events (cardiac events, readmissions, mortality) in a complete cohort of patients undergoing PCI.
• To determine if self-rated health status predicts long-term adverse outcomes following PCI.

Main Methods:

• A cohort of CHD patients treated with PCI was followed using questionnaires and registers.
• Self-rated health was assessed 4 weeks post-PCI using the SF-12 Health Survey.
• Multiple imputation was used to create a complete cohort, including nonrespondents, to mitigate bias.

Main Results:

• Poor self-rated health was significantly associated with increased cardiac events, coronary heart disease-related readmissions, and all-cause mortality.
• The association between poor self-rated health and adverse outcomes was stronger for all-cause mortality compared to cardiac events and readmissions.
• Both physical and mental health components of self-rated health showed an exposure-response pattern with adverse outcomes, with physical health being more impactful.

Conclusions:

• Self-reported health status within 4 weeks of PCI is a significant predictor of adverse cardiovascular outcomes.
• These findings underscore the importance of assessing and addressing self-perceived health in patients post-PCI to identify those at higher risk for adverse events.
• The study highlights the prognostic value of self-rated health in predicting long-term outcomes in patients treated with PCI.