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Published on: July 29, 2021
Vascular risk in migraineurs: interaction of endothelial and cortical excitability factors
Natalia Murinova1, Daniel L Krashin, Sylvia Lucas
1Department of Neurology, University of Washington Medical Center and Harborview Medical Center, Seattle, WA, USA.
Background:
Migraine is a common primary headache disorder occurring predominantly in a young, relatively healthy population.
Results:
There is a growing literature on associations between migraine, especially migraine with aura, and ischemic stroke as well as other vascular events. Migraine as a risk factor for vascular disease and connections between migraine and endothelial, structural, and genetic risk are reviewed.
Conclusion:
There may be an interaction between endothelial dysfunction and cortical spreading depression affecting risk. Patient education and treatment of modifiable risk factors may decrease future vascular events.
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