Related Experiment Videos
An RNA secondary structure workbench
1Department of Biochemistry and Biophysics, University of California, San Franciso 94143.
Nucleic Acids Research
|March 11, 1988
Abstract:
A multiple approach to the study of RNA secondary structure is described which provides for the independent drawing of structures using base-pairing lists, for the generation of local structures in the form of hairpins, and for the generation of global structures by both Monte Carlo and dynamic programming methodologies. User-adjustable parameters provide for limiting the size of hairpin loops, bulges and inner loops, and constraints can be imposed relative to position-dependent base pairing.