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Primary molar pulpotomy: a systematic review and network meta-analysis
Po-Yen Lin1, Hsueh-Szu Chen2, Yu-Hsiang Wang3
1Department of Dentistry, School of Dentistry, National Yang-Ming University, Taipei, Taiwan.
Journal of Dentistry
|February 12, 2014
Summary
Mineral trioxide aggregate (MTA) is the preferred pulpotomy treatment for primary molars, offering superior outcomes. Ferric sulfate is a cost-effective alternative when permanent teeth replacement is anticipated.
Area of Science:
- Dentistry
- Pediatric Dentistry
- Dental Materials
Background:
- Pulpotomy is a standard treatment for reversible pulpitis in primary molars.
- Various materials and techniques are used for pulpotomy, each with distinct clinical and radiographic outcomes.
Purpose of the Study:
- To systematically review and network meta-analyze the clinical and radiographic outcomes of different primary molar pulpotomy procedures.
- To compare formocresol, ferric sulfate, calcium hydroxide, mineral trioxide aggregate (MTA), and laser pulpotomy.
Main Methods:
- Systematic literature search of multiple databases until December 2012.
- Bayesian network meta-analyses comparing treatment failure rates (including premature tooth loss) at 12 and 24 months.
- Inclusion of 37 studies in the review and 22 in the meta-analyses.
Main Results:
- Mineral trioxide aggregate (MTA) demonstrated significantly better clinical and radiographic outcomes compared to calcium hydroxide and laser therapies.
- Formocresol and ferric sulfate also showed superior results to calcium hydroxide and laser treatments.
- Odds ratios indicated higher failure rates for calcium hydroxide and laser therapies versus formocresol, ferric sulfate, and MTA.
Conclusions:
- Mineral trioxide aggregate (MTA) is recommended as the primary choice for pulpotomy in primary molars.
- Ferric sulfate presents a viable, cost-effective alternative, particularly when primary teeth are expected to be exfoliated soon.

