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Gynecomastia in subjects with sexual dysfunction.

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Gynecomastia is rare in men with sexual dysfunction (SD), affecting 3.1%. It

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Area of Science:

  • Endocrinology
  • Andrology
  • Sexual Medicine

Background:

  • Gynecomastia, the enlargement of male breast tissue, can be associated with hormonal imbalances.
  • Sexual dysfunction (SD) is a common concern affecting men's quality of life.
  • Understanding the links between gynecomastia and SD is crucial for diagnosis and treatment.

Purpose of the Study:

  • To investigate the prevalence and clinical significance of gynecomastia in a large cohort of men with sexual dysfunction.
  • To analyze associations between gynecomastia and various clinical, biochemical, and hormonal parameters in men with SD.

Main Methods:

  • Retrospective analysis of 4,023 men attending a sexual dysfunction outpatient clinic.
  • Exclusion of patients with Klinefelter's syndrome.
  • Assessment of clinical parameters, hormone levels (including testosterone), and sexual function complaints.

Main Results:

  • The prevalence of gynecomastia was 3.1% in men with SD (excluding Klinefelter's).
  • Gynecomastia was linked to lower testosterone levels, delayed puberty, testicular/hepatic diseases, cannabis use, and severe obesity.
  • Patients with gynecomastia reported significantly higher rates of erectile dysfunction, lower sexual desire, orgasm difficulties, and reduced ejaculate volume.

Conclusions:

  • Gynecomastia is uncommon in men with sexual dysfunction but warrants further investigation.
  • It may indicate underlying testosterone deficiency or other endocrine/health issues.
  • Early identification and evaluation of gynecomastia in men with SD are important for comprehensive patient care.