Related Experiment Video
Updated: May 3, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Depression and disability in migraine: the role of pain acceptance and values-based action
Lilian Dindo1, Ana Recober, James Marchman
1Department of Psychiatry, University of Iowa College of Medicine, Psychiatry Research MEB 2-203, Iowa City, IA, 52242-1000, USA, lilian-dindo@uiowa.edu.
Background:
Migraine is a complex neurological disorder that substantially impairs a person's functioning and is often comorbid with depression. Currently, little is known about psychological coping strategies that may underlie disability and depression in patients with migraine.
Purpose:
This study examines concurrent relations between depression and disability on the one hand and pain acceptance and values-based action on the other hand in patients with migraine.
Method:
Ninety-three patients with migraine and depressive symptoms-being evaluated for a larger project examining the impact of a behavioral intervention on depression in patients with migraine-completed measures of depression, disability, pain acceptance, and values-based action. Using multiple regression analyses, the contributions of pain acceptance and values-based action to depression and disability were assessed.
Results:
Low pain acceptance was strongly associated with depression and disability (r s(2) = .15-.37) in these patients. Low pain acceptance also explained unique variance in disability, beyond that of depression. Values-based action related modestly to depression and disability (r s(2) = .02-.07).
Conclusion:
Pain acceptance can contribute to our understanding of psychological health and functioning. An important next step would be to examine whether targeting acceptance in treatment of patients with migraine would lead to improvements in their mental health and functioning.
Related Concept Videos
Depressive Disorders: MDD and Dysthymia
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Depression: Overview
Analgesia and Pain Management
Frustration and Conflict: Avoidance-Avoidance, Double-Approach Avoidance
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...

