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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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1,2-Dihydro-2-oxopyridine-3-carboxamides: the C-5 substituent is responsible for functionality switch at CB2

Valentina Lucchesi1, Teija Parkkari2, Juha R Savinainen3

  • 1Dipartimento di Farmacia, Università di Pisa, Via Bonanno 6, 56126 Pisa, Italy.

European Journal of Medicinal Chemistry
|February 13, 2014
PubMed

Keywords:
CB1 receptorCB2 receptorCB2 receptor inverse agonistCB2 receptor neutral antagonistCannabinoid

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