Related Experiment Video
Updated: May 3, 2026

Saccharomyces cerevisiae Exponential Growth Kinetics in Batch Culture to Analyze Respiratory and Fermentative Metabolism
Published on: September 30, 2018
Evaluation of a kinetic model for computer simulation of growth and fermentation by Scheffersomyces (Pichia) stipitis
P J Slininger1, B S Dien, J M Lomont
1Bioenergy Research Unit, National Center for Agricultural Utilization Research, USDA, Agricultural Research Service a, Peoria, Illinois, 61604-3902. pat.slininger@ars.usda.gov.
Abstract:
Scheffersomyces (formerly Pichia) stipitis is a potential biocatalyst for converting lignocelluloses to ethanol because the yeast natively ferments xylose. An unstructured kinetic model based upon a system of linear differential equations has been formulated that describes growth and ethanol production as functions of ethanol, oxygen, and xylose concentrations for both growth and fermentation stages. The model was validated for various growth conditions including batch, cell recycle, batch with in situ ethanol removal and fed-batch. The model provides a summary of basic physiological yeast properties and is an important tool for simulating and optimizing various culture conditions and evaluating various bioreactor designs for ethanol production.
Related Concept Videos
Bioreactor Controls-III
Microbial Growth Measurement: Indirect Methods
Microbial Growth Measurement: Direct Methods

