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Published on: February 7, 2025
Intakes of potassium, magnesium, and calcium and risk of stroke
Ivonne Sluijs1, Sebastien Czernichow, Joline W J Beulens
1From the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands (I.S., J.W.J.B., Y.T.v.d.S., D.E.G.); Department of Nutrition, Assistance Publique-Hôpitaux de Paris, Hôpital A Paré, Université Versailles St-Quentin, Boulogne, France (S.C.); INSERM U1018, Centre for Research in Epidemiology and Population Health, Villejuif, France (S.C.); and Centre for Nutrition, Prevention and Health Services, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands (J.M.A.B., W.M.M.V.).
Background And Purpose:
We aimed to investigate the associations of dietary and total potassium, magnesium, and calcium intakes with stroke occurrence.
Methods:
A prospective cohort study was conducted among 36 094 participants aged 21 to 70 years. Dietary intake was assessed with a food frequency questionnaire.
Results:
During 12 years of follow-up, 631 strokes occurred. After adjustment for confounders, magnesium intake was associated with reduced stroke risk (hazard ratio [95% confidence interval] per 100 mg/d, 0.80 [0.67-0.97] dietary magnesium; 0.78 [0.65-0.93] total magnesium). Potassium and calcium intakes were not associated with stroke.
Conclusions:
This study supports an association between high magnesium intake and a reduced stroke risk.
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