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Related Experiment Video

Updated: May 3, 2026

Optogenetic Entrainment of Hippocampal Theta Oscillations in Behaving Mice

Optogenetic Entrainment of Hippocampal Theta Oscillations in Behaving Mice

Published on: June 29, 2018

Increase in hippocampal theta oscillations during spatial decision making.

Hindiael Belchior¹, Vítor Lopes-Dos-Santos, Adriano B L Tort

¹Brain Institute, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil; Psychobiology Graduate Program, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.

|February 13, 2014

Summary

Hippocampal theta oscillations (5-12 Hz) are crucial for spatial decision-making in rats. This study found theta power and frequency increased during decisions, especially correct ones, even when controlling for locomotion speed.

Keywords:

LFP locomotion oscillations radial maze spatial choice speed

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Automatic Detection of Highly Organized Theta Oscillations in the Murine EEG

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Related Experiment Videos

Last Updated: May 3, 2026

Optogenetic Entrainment of Hippocampal Theta Oscillations in Behaving Mice

Optogenetic Entrainment of Hippocampal Theta Oscillations in Behaving Mice

Published on: June 29, 2018

Tuning in the Hippocampal Theta Band In Vitro: Methodologies for Recording from the Isolated Rodent Septohippocampal Circuit

Tuning in the Hippocampal Theta Band In Vitro: Methodologies for Recording from the Isolated Rodent Septohippocampal Circuit

Published on: August 2, 2017

Automatic Detection of Highly Organized Theta Oscillations in the Murine EEG

Automatic Detection of Highly Organized Theta Oscillations in the Murine EEG

Published on: March 10, 2017

Area of Science:

Neuroscience
Cognitive Science
Behavioral Neuroscience

Background:

Hippocampal theta oscillations (5-12 Hz) are implicated in spatial and mnemonic processing.
Locomotor activity confounds the study of theta oscillations' cognitive roles.
Previous research suggests theta oscillations support decision-making.

Purpose of the Study:

To investigate the modulation of hippocampal theta oscillations during spatial decision-making.
To control for locomotion speed as a confounding factor.
To determine if theta activity differs between correct and incorrect choices.

Main Methods:

Recorded local field potentials from the CA1 region of rats in a four-arm radial maze task.
Analyzed theta oscillations during decision-making, intertrial delay, and running periods.
Performed speed-controlled analyses to isolate cognitive effects.

Main Results:

Prominent theta oscillations were observed during the decision-making period.
Theta power and frequency were significantly higher during decision-making compared to delay or running periods (speed-controlled).
Theta activity was elevated during decision periods preceding correct choices versus incorrect choices.

Conclusions:

Hippocampal theta oscillations play a significant role in spatial decision-making.
The findings support a cognitive function for theta rhythm in choice selection.
Controlling for locomotion speed strengthens the link between theta and decision processes.