Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Comparing Intermolecular Forces: Melting Point, Boiling Point, and Miscibility02:34

Comparing Intermolecular Forces: Melting Point, Boiling Point, and Miscibility

42.6K
Intermolecular forces are attractive forces that exist between molecules. They dictate several bulk properties, such as melting points, boiling points, and solubilities (miscibilities) of substances. Molar mass, molecular shape, and polarity affect the strength of different intermolecular forces, which influence the magnitude of physical properties across a family of molecules.
Temporary attractive forces like dispersion are present in all molecules, whether they are polar or nonpolar. They...
42.6K
Intermolecular Forces and Physical Properties02:56

Intermolecular Forces and Physical Properties

23.2K
23.2K
Nonideal Two-Component Liquid Solutions01:29

Nonideal Two-Component Liquid Solutions

137
Nonideal liquid solutions, also known as real solutions, do not strictly follow Raoult's law. Raoult's law is a rule of thumb in physical chemistry. However, not all mixtures adhere to this law due to varying molecular interactions. For example, in an acetone/chloroform solution, the individual vapor pressures of the components are lower than expected, resulting in a total vapor pressure below that predicted by Raoult's law, causing a negative deviation.On the other hand, in an ethanol/water...
137
Two Components: Liquid–Liquid Systems01:27

Two Components: Liquid–Liquid Systems

172
A pressure-composition phase diagram explicitly describes the behavior of an ideal solution of two volatile liquids under varying pressures and compositions. A pressure-composition diagram has two main curves. The bubble point curve represents the plot of pressure versus liquid mole fraction. It indicates the pressure at which the first bubble of vapor forms from the liquid phase as the system pressure decreases.The dew point curve is the pressure versus vapor mole fraction. It indicates the...
172
Distillation: Vapor–Liquid Equilibria01:01

Distillation: Vapor–Liquid Equilibria

4.1K
Distillation is a separation technique that takes advantage of the boiling point properties of disparate elements in a mixture. To perform distillation, we begin by heating a miscible mixture of two liquids with a significant difference in boiling points (at least 20°C). As the solution heats up and reaches the bubble point of the more volatile component, some molecules of the more volatile component transition into the gas phase and travel upward into the condenser, which is a glass tube...
4.1K
Ideal Solutions or Mixtures01:20

Ideal Solutions or Mixtures

128
From a molecular perspective, an ideal solution is one in which the intermolecular interactions between unlike molecules are, on average, the same as those between like molecules. This is the case for ideal gas mixtures, where the molecules are far apart and do not interact with each other. However, for condensed phases like liquids or solids, the molecules are close together and interact with each other. In an ideal solution, the molecules of different species are so similar to each other that...
128

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Computer-assisted adenoma detection colonoscopy with an ENDO-AID artificial intelligence system and Endocuff- versus Endocuff-assisted colonoscopy: A randomized controlled trial.

Gastroenterologia y hepatologia·2026
Same author

Adsorption of Imidazolium-Based ILs Combined on Activated Carbon Obtained from Grape Seeds.

Molecules (Basel, Switzerland)·2025
Same author

Behaviour of dichloromethane in solution with hydrocarbons and esters using a database with properties generated in the mixing processes.

Data in brief·2025
Same author

Assessment of Scalable Fractionation Methodologies to Produce Concentrated Lauric Acid from Black Soldier Fly (<i>Hermetia illucens</i>) Larvae Fat.

Insects·2025
Same author

A comprehensive database showing quantitative mixing effects related to volume and enthalpy in systems of dibromomethane with alkylalkanoates and with alkanes.

Data in brief·2024
Same author

An Insight into the Molecular Electronic Structure of Graphene Oxides and Their Interactions with Molecules of Different Polarities Using Quantum Chemical and COSMO-RS Calculations.

Molecules (Basel, Switzerland)·2024

Related Experiment Video

Updated: May 3, 2026

Analyzing Mixing Inhomogeneity in a Microfluidic Device by Microscale Schlieren Technique
10:12

Analyzing Mixing Inhomogeneity in a Microfluidic Device by Microscale Schlieren Technique

Published on: June 12, 2015

8.7K

Ionic liquid mixtures--an analysis of their mutual miscibility.

Salama Omar1, Jesus Lemus, Elia Ruiz

  • 1Sección de Ingeniería Química (Departamento de Química Física Aplicada), Universidad Autónoma de Madrid , Cantoblanco, 28049 Madrid, Spain.

The Journal of Physical Chemistry. B
|February 14, 2014
PubMed
Summary

Ionic liquid mixtures (IL-IL) offer tunable solvent properties. This study computationally explores IL-IL mixing behavior, identifying guidelines for designing immiscible IL-IL systems, particularly those based on imidazolium compounds.

More Related Videos

Synthesis of Ionic Liquid Based Electrolytes, Assembly of Li-ion Batteries, and Measurements of Performance at High Temperature
11:04

Synthesis of Ionic Liquid Based Electrolytes, Assembly of Li-ion Batteries, and Measurements of Performance at High Temperature

Published on: December 20, 2016

12.4K
Development, Characterization, and Evaluation of CAGE-based Ionic Liquid Systems for Transdermal Delivery
09:44

Development, Characterization, and Evaluation of CAGE-based Ionic Liquid Systems for Transdermal Delivery

Published on: September 26, 2025

811

Related Experiment Videos

Last Updated: May 3, 2026

Analyzing Mixing Inhomogeneity in a Microfluidic Device by Microscale Schlieren Technique
10:12

Analyzing Mixing Inhomogeneity in a Microfluidic Device by Microscale Schlieren Technique

Published on: June 12, 2015

8.7K
Synthesis of Ionic Liquid Based Electrolytes, Assembly of Li-ion Batteries, and Measurements of Performance at High Temperature
11:04

Synthesis of Ionic Liquid Based Electrolytes, Assembly of Li-ion Batteries, and Measurements of Performance at High Temperature

Published on: December 20, 2016

12.4K
Development, Characterization, and Evaluation of CAGE-based Ionic Liquid Systems for Transdermal Delivery
09:44

Development, Characterization, and Evaluation of CAGE-based Ionic Liquid Systems for Transdermal Delivery

Published on: September 26, 2025

811

Area of Science:

  • Physical Chemistry
  • Materials Science
  • Chemical Engineering

Background:

  • Ionic liquid mixtures (IL-IL) are explored for precise solvent property tuning.
  • Existing studies show diverse mixing behaviors, from ideal to nonideal, influenced by IL component structures.
  • Controlling miscibility in IL-IL systems is crucial for solvent design.

Purpose of the Study:

  • To systematically investigate the mixing behavior of binary IL-IL systems using computational methods.
  • To analyze the impact of cation-anion interactions on IL-IL miscibility.
  • To develop guidelines for predicting and designing IL-IL mixtures with specific phase behaviors.

Main Methods:

  • Utilized the COSMO-RS (Conductor-like Screening Model for Real Solvents) methodology for computational analysis.
  • Calculated liquid-liquid equilibrium (LLE) and excess enthalpy (H(E)) data for over 200 binary IL-IL mixtures.
  • Included various ILs based on imidazolium, pyridinium, pyrrolidinium, ammonium, and phosphonium cations.

Main Results:

  • Calculated LLE and H(E) data for a wide range of IL-IL mixtures across different temperatures.
  • Analyzed the influence of specific cation-anion interactions on the miscibility of IL-IL systems.
  • Identified a novel class of immiscible IL-IL mixtures composed exclusively of imidazolium-based ILs.

Conclusions:

  • The COSMO-RS methodology provides a reliable approach to predict IL-IL mixing behavior.
  • Understanding cation-anion interactions is key to controlling miscibility in IL-IL mixtures.
  • New immiscible IL-IL systems, particularly imidazolium-based ones, have been identified, expanding solvent design possibilities.