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Related Experiment Videos

Milk fever: a case against polypharmacy solutions.

P A Mullen

    The Veterinary Record
    |November 12, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Higher calcium doses effectively treat hypocalcaemia (parturient paresis) in cattle. Treatments with 8g calcium were superior to 6.2g, with fewer relapses, and added magnesium showed no benefit.

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    An investigation of the toxicity of 1alpha-hydroxycholecalciferol to calves.

    Research in veterinary science·1979

    Area of Science:

    • Veterinary Medicine
    • Animal Science
    • Biochemistry

    Background:

    • Hypocalcaemia, commonly known as parturient paresis or milk fever, is a metabolic disorder affecting cattle.
    • It is characterized by low blood calcium levels, particularly around calving.
    • Effective treatment is crucial for animal welfare and farm economics.

    Purpose of the Study:

    • To compare the efficacy of different intravenous calcium salt solutions for treating hypocalcaemia in cattle.
    • To evaluate the impact of added magnesium on treatment outcomes.
    • To assess the clinical and biochemical responses to varying calcium dosages.

    Main Methods:

    • A comparative study involving 134 cases of hypocalcaemia in cattle across 72 herds in the UK and Eire.
    • Intravenous administration of three different calcium salt solutions: two containing 8g calcium (one with added magnesium) and one containing 6.2g calcium.

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  • Monitoring of biochemical and clinical responses 24 hours post-treatment and assessment of relapse rates.

    • Main Results:

    • Biochemical responses were similar across all tested calcium solutions 24 hours after treatment.
    • Clinical responses to the 8g calcium solutions were significantly better than the 6.2g solution (P<0.02).
    • A higher relapse rate (44%) was observed in cases treated with the 6.2g calcium solution. Added magnesium did not improve clinical outcomes.

    Conclusions:

    • Intravenous administration of 8g calcium is more effective for treating hypocalcaemia (parturient paresis) in cattle than 6.2g calcium.
    • The addition of magnesium to calcium solutions does not appear to enhance clinical recovery from parturient paresis.
    • Optimizing calcium dosage is key to reducing relapse rates in affected cattle.