Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Bipolar Disorder

Bipolar Disorder

Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.

Anxiety: Overview

Anxiety: Overview

Anxiety is a common mental disorder featuring excessive worry, fear, and apprehension, significantly affecting daily life. People with anxiety disorders experience persistent and intense anxiety, interrupting their everyday functioning.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.

Panic Disorder

Panic Disorder

Panic disorder is an anxiety disorder characterized by recurrent and sudden minutes-long episodes of intense fear, known as panic attacks. These attacks may feel like heart attacks and often happen without warning or a specific cause. They can include symptoms such as rapid heart rate, shortness of breath, chest pain, trembling, sweating, dizziness, and a sense of helplessness. During a panic attack, individuals may feel as though they are experiencing a heart attack or are in a...

Social Anxiety Disorder

Social Anxiety Disorder

Social anxiety disorder, also known as social phobia, is characterized by an intense fear of social situations where one might face humiliation, rejection, embarrassment, or negative evaluation. This disorder leads individuals to avoid activities like casual conversations, public speaking, or seemingly simple tasks such as eating, signing documents, or swimming, in public settings. Its impact extends beyond discomfort, often significantly interfering with daily functioning and quality of life.

Generalized Anxiety Disorder

Generalized Anxiety Disorder

Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry that persists for at least six months, significantly interfering with daily functioning. Unlike situational anxiety, which arises in response to specific stressors, GAD often occurs without a clear cause. Individuals may experience disproportionate worry about work, health, or relationships. For instance, a person might continuously fear poor health despite normal medical evaluations or...

Stress and Mental Health

Stress and Mental Health

Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Baseline inflammatory markers, CPAP adherence, impacts on cardiovascular events, and mortality in obstructive sleep apnea: retrospective naturalistic study.

Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia·2026

Same authorSame journal

Toxic masculinity and depression in men: A schema therapy perspective.

Neuro endocrinology letters·2026

Same author

Integrating Existential Perspectives into Schema Therapy: A Conceptual Framework with Clinical Illustrations.

Psychology research and behavior management·2026

Same author

Psychedelics and neurostimulation for treatment resistant psychiatric disorders.

Discover mental health·2026

Same author

Developing kind parent mode in schema therapy and supervisions.

Neuro endocrinology letters·2026

Same author

Correlates of Anti-Toxoplasma IgG Antibodies in Females with Borderline Personality Disorder: A Pilot Cross-Sectional Study.

Neuropsychiatric disease and treatment·2026

Search research articles

Related Experiment Video

Updated: May 3, 2026

A New Method for Inducing a Depression-Like Behavior in Rats

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

Bipolar disorder and anxiety disorders.

Klara Latalova¹, Jan Prasko², Ales Grambal²

¹Department of Psychiatry, Faculty of Medicine and Dentistry, University Palacky Olomouc, University Hospital Olomouc, Czech Republic. klaralat@centrum.cz.

Neuro Endocrinology Letters

|February 14, 2014

Summary

Comorbid anxiety disorders in bipolar disorder patients are linked to worse outcomes, including shorter euthymia periods and increased suicidal ideation. Further research is needed to understand anxiety

More Related Videos

Developing a Rat Model for Bipolar Disorder

Developing a Rat Model for Bipolar Disorder

Published on: May 2, 2025

Social Isolation Model: A Noninvasive Rodent Model of Stress and Anxiety

Social Isolation Model: A Noninvasive Rodent Model of Stress and Anxiety

Published on: November 11, 2022

Related Experiment Videos

Last Updated: May 3, 2026

A New Method for Inducing a Depression-Like Behavior in Rats

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

Developing a Rat Model for Bipolar Disorder

Developing a Rat Model for Bipolar Disorder

Published on: May 2, 2025

Social Isolation Model: A Noninvasive Rodent Model of Stress and Anxiety

Social Isolation Model: A Noninvasive Rodent Model of Stress and Anxiety

Published on: November 11, 2022

Area of Science:

Psychiatry
Clinical Psychology

Background:

Anxiety disorders frequently co-occur with bipolar disorder.
Comorbidity significantly impacts disease progression and treatment efficacy.

Purpose of the Study:

To review the literature on the impact of anxiety disorders in bipolar disorder patients.
To identify outcomes associated with comorbid anxiety in bipolar disorder.

Main Methods:

Systematic literature searches were performed using keywords like "bipolar disorder" and "anxiety disorders".
Studies were sourced from MEDLINE (1970-2012) and reference lists of relevant articles.

Main Results:

Patients with bipolar disorder and comorbid anxiety disorders experience poorer outcomes.
These include shorter periods of euthymia, increased suicidal thoughts, and more suicide attempts.
The effectiveness of anxiety treatment on bipolar disorder outcomes remains unestablished, with a lack of intervention studies.

Conclusions:

Anxiety disorders significantly influence the course and outcomes of bipolar disorder.
Further research is warranted to elucidate the precise impact of anxiety on bipolar disorder and to develop targeted interventions.