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Updated: May 3, 2026

Isolation and Excision of Murine Aorta; A Versatile Technique in the Study of Cardiovascular Disease
Published on: November 24, 2014
The anatomy of the aging aorta
Jarrod A Collins1, Julie-Vanessa Munoz, Toral R Patel
1Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee.
Abstract:
Age-associated changes to aortic anatomy and physiology have an effect on hemodynamics and play a large role in the genesis of cardiovascular pathologies including atherosclerosis, congestive heart failure, and aortic aneurysm. Despite their recognized role in hemodynamics, the complete mechanism for aortic aging is still not clear and their full effects on cardiovascular pathologies are unknown. This article serves as a review of the normal anatomy of the human aorta and its known age-associated changes.
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