Related Experiment Video
Updated: May 3, 2026
Author Spotlight: Enhancing Graft Viability Assessment Through Quantitative Metrics and Innovative Reservoir Systems
Published on: August 2, 2024
Potassium concentration on admission is an independent risk factor for target lesion revascularization in acute
Tsuyoshi Honda1, Kazuteru Fujimoto1, Yuji Miyao1
1Department of Cardiology, Cardiovascular Center, National Hospital Organization Kumamoto Medical Center, 1-5 Ninomaru, Chuo-ku, Kumamoto 860-0008, Japan.
Insights
Higher admission potassium levels in acute myocardial infarction (AMI) patients predict target lesion revascularization (TLR) after bare metal stent intervention. This finding aids in identifying patients at increased risk for repeat procedures.
Area of Science:
- Cardiology
- Interventional Cardiology
- Clinical Research
Background:
- Acute myocardial infarction (AMI) involves catecholamine excess and potential hypokalemia.
- Adrenergic receptor gene variations are linked to target lesion revascularization (TLR) post-coronary intervention.
Purpose of the Study:
- To investigate the association between admission serum potassium levels and TLR in AMI patients undergoing coronary intervention.
Main Methods:
- 276 consecutive AMI patients within 24 hours of symptom onset were enrolled.
- Patients underwent emergency bare metal stent intervention.
- Serum potassium levels on admission were categorized into tertiles (low, mid, high).
- A 5-10 month follow-up period was used to assess TLR.
Main Results:
- Sixty-four instances of TLR were recorded.
- Elevated serum potassium concentration on admission was significantly associated with TLR.
- Patients in the highest potassium tertile had a 2.5-fold increased likelihood of TLR compared to the lowest tertile.
- Admission potassium level independently predicted TLR (OR 1.69, P=0.036).
Conclusions:
- Increased admission potassium levels may serve as a predictive marker for TLR in AMI patients treated with bare metal stents.
Background:
Acute myocardial infarction (AMI) is accompanied by excessive production of catecholamines, which is characterized by a hypokalemic dip. A polymorphism of the adrenergic receptor has also been reported to be associated with target lesion revascularization (TLR) after coronary intervention.
Subjects And Methods:
We enrolled 276 consecutive patients with AMI within 24 hours of symptom onset, who underwent emergency coronary intervention using bare metal stents and had examinations over a 5-10-month follow-up period. The patients were divided into tertiles based on their serum potassium level on admission (low K, <3.9; mid K, ≥ 3.9, <4.3; and high K, ≥ 4.3).
Results:
Sixty-four TLRs were observed in the study. Increased potassium concentration was associated significantly with TLR. Patients in the high K group were about two and a half times more likely to have a TLR after AMI compared to those in the low K group. Multiple logistic analysis showed that potassium level on admission was an independent risk factor for TLR (odds ratio 1.69; confidence interval 1.04 to 2.74; P = 0.036).
Conclusions:
These findings indicated that increased potassium levels on admission might predict TLRs in AMI patients treated with bare metal stents.
More Related Videos
Related Concept Videos
01:20Acute Kidney Injury V: Interprofessional Care
01:30Acute Kidney Injury IV: Diagnostic Studies and Prevention
01:22Acute Kidney Injury I: Introduction
01:28Cardiac Catheterization I: Pre-Procedure Overview
01:22Acute Kidney Injury VI: Nursing Management
01:28Antihypertensive Drugs: Potassium-Sparing Diuretics