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Fulminant mucormycosis involving paranasal sinuses: a rare case report
Komali Garlapati1, Sunanda Chavva2, Rahul Marshal Vaddeswarupu2
1Department of Oral Medicine and Radiology, Room No. 1, Panineeya Mahavidyalaya Institute of Dental Sciences and Research Centre, Road No. 5, Kamalanagar, Dilsukhnagar, Hyderabad, Andhra Pradesh 500060, India.
Abstract:
Mucormycosis is an opportunistic fulminant fungal infection, which has the ability to cause significant morbidity and frequently mortality in the susceptible patient. Common predisposing factors include diabetes mellitus and immunosuppression. The infection begins in the nose and paranasal sinuses due to inhalation of fungal spores. The fungus invades the arteries leading to thrombosis that subsequently causes necrosis of the tissue. The infection can spread to orbital and intracranial structures either by direct invasion or through the blood vessels. Here we describe a case of mucormycosis of maxillary antrum extending to ethmoidal and frontal sinus and also causing necrosis of left maxilla in an uncontrolled diabetic individual to emphasize early diagnosis and treatment of this fatal fungal infection.
Insights
Mucormycosis is a severe fungal infection often fatal in immunocompromised patients. Early diagnosis and treatment are crucial for managing this invasive sinus infection, especially in uncontrolled diabetics.
Area of Science:
- Mycology
- Infectious Diseases
- Otolaryngology
Background:
- Mucormycosis is a rare but life-threatening opportunistic fungal infection.
- It commonly affects individuals with diabetes mellitus and immunosuppression.
- Infection typically originates in the nasal and paranasal sinuses following spore inhalation.
Purpose of the Study:
- To report a case of extensive mucormycosis in an uncontrolled diabetic patient.
- To highlight the importance of early diagnosis and prompt treatment of mucormycosis.
- To illustrate the potential for rapid tissue necrosis and spread of infection.
Main Methods:
- Case report of a patient with mucormycosis.
- Clinical presentation and diagnostic findings.
- Treatment and outcome.
Main Results:
- The patient, an uncontrolled diabetic, presented with mucormycosis of the maxillary antrum.
- The infection extended to the ethmoidal and frontal sinuses.
- Necrosis of the left maxilla was observed, indicating aggressive disease progression.
Conclusions:
- Mucormycosis can lead to severe morbidity and mortality, particularly in diabetic patients.
- Prompt medical and surgical intervention is essential for favorable outcomes.
- This case underscores the need for heightened clinical suspicion and timely management.
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