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Updated: May 3, 2026

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
Published on: April 20, 2018
Multidisciplinary treatment approach in a patient with history of nasopharyngeal carcinoma
Atacan Yavuz1, Omer Birkan Ağralı1, Zeynep Lale Calışkan2
1Department of Periodontology, Faculty of Dentistry, Marmara University, Nişantaşı Kampusu, Büyükçiftlik Sok. No. 8, Nişantaşı-Şişli, 34365 Istanbul, Turkey.
Abstract:
Radiotherapy in NPC patients has side effects on the dentition, which affects quality of life dramatically. This case report presents multidisciplinary dental treatment approach in a 17-year-old male patient with a history of nasopharyngeal carcinoma (NPC), which was treated with chemotherapy and radiotherapy. The adolescent patient applied to dental hospital 4 years after the radiotherapy with aesthetic and functional problems on dentition affecting psychological, social, and physical aspects of his life. The dentition of the patient demonstrated the severe destruction as a devastating side effect of radiotherapy. With a successful multidisciplinary approach, our patient's aesthetics, function, and self-confidence were obtained. Well-established procedures, which include preventative care and maintenance, can reduce the duration and expenses of the treatment and help in challenging the life-long complications of radiotherapy.
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