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Updated: May 3, 2026
Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications
Published on: August 28, 2015
The properties of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) and its applications in tissue engineering
Qixiang Yang, Jing Wang, Shu Zhang
1Department of Stomatology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, No. 301., Middle Yanchang Road, Shanghai 200072, P.R. China. raoraowang@tongji.edu.cn.
Abstract:
Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) is a member of the polyhydroxyalkanoate (PHA) family. It is the designation of molecules consisting of random co-polymers of 3-hydroxybutyrate and 3- hydroxyhexanoate. PHBHHx plays a significant role in the field of biomedical materials. It has good physical, chemical and mechanical properties, making it potentially useful for a wide range of biomaterials applications. In addition, it has also shown better biocompatibility with different cell types. This paper will introduce the physical, chemical and biological properties of PHBHHx, including biodegradation, hydrophilicity, surface properties and cytocompatibility. The development of PHBHHx in tissue-engineering applications will be discussed. PHBHHx used to repair bone, cartilage, tendons, nerves and vessels will be the focus of discussion.
