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Adenocarcinoma of the appendix
C C Conte1, N J Petrelli, J Stulc
1Department of Surgical Oncology, Roswell Park Memorial Institute, Buffalo, New York 14263.
Surgery, Gynecology & Obstetrics
|May 1, 1988
Summary
Right hemicolectomy is the recommended treatment for appendix adenocarcinoma, improving survival rates. Ovarian metastases are common in women, and palliative oophorectomy may prolong survival.
Area of Science:
- Oncology
- Surgical Oncology
- Gastrointestinal Oncology
Background:
- Adenocarcinoma of the appendix is a rare malignancy.
- Understanding its presentation and treatment outcomes is crucial for patient management.
Purpose of the Study:
- To review treatment outcomes for adenocarcinoma of the appendix.
- To determine the optimal surgical approach and management of metastatic disease.
Main Methods:
- Retrospective review of 16 patients with adenocarcinoma of the appendix treated between 1964 and 1986.
- Analysis of tumor characteristics, metastasis patterns, and survival rates based on surgical intervention.
Main Results:
- Mucinous histology (13/15) and well-differentiated tumors (10/15) were common.
- Metastatic disease was present in 11 patients, frequently as carcinomatosis (9/11).
- Ovarian metastases occurred in 7/8 women; 9/11 metastatic patients presented with symptoms related to metastases.
- Five-year survival was 50% with right hemicolectomy versus 25% with appendectomy.
Conclusions:
- Right hemicolectomy is the preferred surgical treatment for adenocarcinoma of the appendix.
- Palliative oophorectomy should be considered for patients with ovarian metastases due to prolonged survival and symptomatic disease.