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Absolute configurations of new limonoids from a Krishna mangrove, Xylocarpus granatum
Wenping Chen1, Li Shen2, Minyi Li2
1Key Laboratory of Marine Bio-resources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, PR China; University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing 100049, PR China.
Abstract:
Four new limonoids, named granatumins V-Y (1-4), belonging to the small group of limonoids with a C1-C29 oxygen bridge and a ∆(8,30) double bond, were isolated from the seeds of an Indian mangrove, Xylocarpus granatum, collected in the swamp of Krishna estuary, Andhra Pradesh. The constitutions and absolute configurations of these compounds were established by extensive NMR investigations, single-crystal X-ray crystallography using Cu Kα radiation, and by the comparison of circular dichroism spectrum.
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