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Updated: May 3, 2026

Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
Published on: January 20, 2023
Sleep disturbance in traumatic brain injury: pharmacologic options
R D Zafonte1, N R Mann1, N L Fichtenberg1
1Rehabilitation Institute of Michigan, Wayne State University, 261 Mack Blvd., Detroit, MI 48201, USA.
Abstract:
The role of sleep disturbance in the behavioral and functional sequelae following Traumatic Brain Injury is becoming increasingly well understood. Sleep disturbances occurs commonly in Traumatic Brain injury patients. Survivors of Traumatic Brain Injury may experience sleep dysfunction during all stages of recovery. An effective understanding of the pathophysiology of sleep disturbance and the role medications play in both causation and treatment is essential for facilitation of rehabilitation management and functional recovery.
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