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Updated: May 3, 2026

Direct Mouse Trauma/Burn Model of Heterotopic Ossification
Published on: August 6, 2015
Heterotopic intra-abdominal ossification in a complex ventral hernia defect
A Obeid1, Ka Sarhane2, T Berjaoui3
1MD, Department of Surgery, University of Alabama, Birmingham, US.
Heterotopic ossification rarely affects abdominal wounds. This case details successful surgical repair of mesenteric ossification and complex abdominal wall reconstruction after penetrating trauma.
Area of Science:
- Orthopaedic Surgery
- Gastrointestinal Surgery
Background:
- Heterotopic ossification (HO) is common in joints but rare in abdominal wounds and mesentery.
- Mesenteric ossification is typically linked to severe intra-abdominal injuries and complications.
Observation:
- A patient presented with intra-abdominal HO and mesenteric involvement post-penetrating trauma.
- The patient had undergone multiple laparotomies, resulting in a complex abdominal wall hernia with loss of domain and enterocutaneous fistulae.
Findings:
- Surgical resection of bony deposits and fistula excision were performed.
- Abdominal wall reconstruction utilized component separation technique and a biologic mesh graft.
Implications:
- This case highlights a rare presentation of HO and its management challenges.
- Successful reconstruction demonstrates a viable approach for complex abdominal wall defects with mesenteric ossification.
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