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High prevalence of serum antibodies to reverse transcriptase in HIV-1-infected individuals
A L DeVico1, F D Veronese, S L Lee
1Department of Cell Biology, Bionetics Research, Inc., Rockville, MD.
AIDS Research and Human Retroviruses
|February 1, 1988
Abstract:
The HIV immunoblot profiles of 700 HIV-antibody-positive sera were examined to determine the frequency of antibody reactivity with p66/p51, the reverse transcriptase of HIV. We report a remarkably high seroprevalence of antibodies to p66/p51, detected in 79% of the sera. Only gp41 is recognized more frequently in these assays. The level of anti-p66/p51 seroreactivity varies only slightly among the clinical stages of HIV infection.