Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diazonium Group Substitution: –OH and –H01:19

Diazonium Group Substitution: –OH and –H

1.9K
Nitrous acid, a weak acid, is prepared in situ via the reaction of sodium nitrite with a strong acid under cold conditions. This nitrous acid prepared in situ reacts with primary arylamines to form arenediazonium salts. Such reactions are known as diazotization reactions. As shown in Figure 1, the formation of arenediazonium salts begins with the decomposition of nitrous acid in an acidic solution to give nitrosonium ions.
1.9K
Acidity and Basicity of Alcohols and Phenols02:36

Acidity and Basicity of Alcohols and Phenols

20.4K
Like water, alcohols are weak acids and bases. This is attributed to the polarization of the O–H bond making the hydrogen partially positive. Moreover, the electron pairs on the oxygen atom of alcohol make it both basic and nucleophilic. Protonation of an alcohol converts hydroxide, a poor leaving group, into water—a good one. The two acid–base equilibria corresponding to ethanol are depicted below.
20.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Increased expression of autophagy-related proteins in keratocystic odontogenic tumours: its possible association with growth potential.

The British journal of oral & maxillofacial surgery·2014
Same author

Inhibition of Akt reverses the acquired resistance to sorafenib by switching protective autophagy to autophagic cell death in hepatocellular carcinoma.

Molecular cancer therapeutics·2014
Same author

The sabotage of the bacterial transcription machinery by a small bacteriophage protein.

Bacteriophage·2014
Same author

In vivo and in vitro evidence of the sex-dependent pharmacokinetics and disposition of G004, a potential hypoglycemic agent, in rats.

European journal of drug metabolism and pharmacokinetics·2014
Same author

Inositol pyrophosphates mediate the effects of aging on bone marrow mesenchymal stem cells by inhibiting Akt signaling.

Stem cell research & therapy·2014
Same author

Sequential release of autophagy inhibitor and chemotherapeutic drug with polymeric delivery system for oral squamous cell carcinoma therapy.

Molecular pharmaceutics·2014

Related Experiment Video

Updated: May 3, 2026

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS
06:34

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS

Published on: June 20, 2014

13.6K

4-Nitro-phenyl-hydrazinium picrate monohydrate.

Hong-Lan Cai1, Bing Liu1, Qing-An Qiao1

  • 1School of Chemistry and Material Science, Ludong University, Yantai 264025, People's Republic of China.

Acta Crystallographica. Section E, Structure Reports Online
|February 15, 2014
PubMed
Summary

This study details the crystal structure of a compound, revealing a two-dimensional network formed by hydrogen bonds. The nitro groups exhibit distinct twists and dihedral angles relative to their ring planes.

More Related Videos

Preparation and Reactivity of a Triphosphenium Bromide Salt: A Convenient and Stable Source of PhosphorusI
08:46

Preparation and Reactivity of a Triphosphenium Bromide Salt: A Convenient and Stable Source of PhosphorusI

Published on: November 22, 2016

7.3K
Determination of the Photoisomerization Quantum Yield of a Hydrazone Photoswitch
09:33

Determination of the Photoisomerization Quantum Yield of a Hydrazone Photoswitch

Published on: February 7, 2022

3.3K

Related Experiment Videos

Last Updated: May 3, 2026

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS
06:34

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS

Published on: June 20, 2014

13.6K
Preparation and Reactivity of a Triphosphenium Bromide Salt: A Convenient and Stable Source of PhosphorusI
08:46

Preparation and Reactivity of a Triphosphenium Bromide Salt: A Convenient and Stable Source of PhosphorusI

Published on: November 22, 2016

7.3K
Determination of the Photoisomerization Quantum Yield of a Hydrazone Photoswitch
09:33

Determination of the Photoisomerization Quantum Yield of a Hydrazone Photoswitch

Published on: February 7, 2022

3.3K

Area of Science:

  • Crystallography
  • Supramolecular Chemistry
  • Materials Science

Background:

  • Understanding the intermolecular interactions and structural arrangements of organic salts is crucial for materials science.
  • Hydrogen bonding plays a significant role in dictating crystal packing and network formation.

Purpose of the Study:

  • To elucidate the crystal structure of the title compound (C6H8N3O2 (+)·C6H2N3O7 (-)·H2O).
  • To analyze the hydrogen bonding patterns and the conformational characteristics of the nitro groups within the crystal lattice.

Main Methods:

  • Single-crystal X-ray diffraction was employed to determine the three-dimensional crystal structure.
  • Analysis of hydrogen bond distances and angles, as well as dihedral angles of nitro groups, was performed.

Main Results:

  • The crystal structure reveals a two-dimensional network facilitated by N-H⋯O and O-H⋯O hydrogen bonds, oriented parallel to the (010) plane.
  • Weak C-H⋯O hydrogen bonds were also identified within the network.
  • Nitro groups in the anion show twists of 1.6(3)°, 7.8(3)°, and 12.1(3)° from the ring plane, while the cation's nitro group has a dihedral angle of 4.6(2)°.

Conclusions:

  • The hydrogen bonding network dictates the supramolecular architecture of the title compound.
  • The observed twists and dihedral angles of the nitro groups provide insights into the electronic and steric effects within the crystal structure.