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Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines
Published on: June 23, 2019
5-(3,5-Di-fluoro-phen-yl)-1-(4-fluoro-phen-yl)-3-tri-fluoro-methyl-1H-pyrazole
Karikere Ekanna Manoj Kumar1, Parameshwar Adimoole Suchetan1, Bandrehalli Siddagangaiah Palakshamurthy2
1Department of Studies and Research in Chemistry, U.C.S., Tumkur University, Tumkur, Karnataka 572 103, India.
Abstract:
In the title compound, C16H8F6N2, the dihedral angle between the pyrazole and di-fluoro-benzene rings is 50.30 (13)°, while those between the pyrazole and fluoro-benzene rings and between the di-fluoro-benzene and fluoro-benzene rings are 38.56 (13) and 53.50 (11)°, respectively. Aromatic π-π stacking inter-actions between adjacent di-fluoro-benzene rings [centroid-centroid separation = 3.6082 (11) Å] link the mol-ecules into dimers parallel to [21-2].
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