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Updated: May 3, 2026

A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
Published on: August 16, 2018
(E)-2-Methyl-3-phenyl-selanyl-4-(phenyl-sulfin-yl)oct-3-en-2-ol
1College of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing 210009, People's Republic of China ; National Engineering Technique Research Center for Biotechnology, Nanjing 211816, People's Republic of China.
Abstract:
In the title compound, C21H26O2SSe, the S atom adopts a pyramidal geometry (bond-angle sum = 304°) and the n-butyl chain shows an extended conformation. An intra-molecular C-H⋯O hydrogen bond closes an S(8) ring. In the crystal, inversion dimers are formed with molecules linked by pairs of O-H⋯O=S hydrogen bonds, generating R 2 (2)(14) loops. Weak C-H⋯O inter-actions also occur.
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