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Updated: May 3, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
1-(1-Benzo-furan-2-yl)ethanone O-(2,6-di-fluoro-benz-yl)oxime
Tomasz Kosmalski1, Andrzej K Gzella2
1Department of Organic Chemistry, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, ul. A. Jurasza 2, 85-089 Bydgoszcz, Poland.
Abstract:
In the title compound, C17H13F2NO2, the 2,2-di-fluoro-benz-yloxy residue assumes an E configuration with respect to the benzo-furan system. The benzene ring makes a dihedral angle of 61.70 (4)° with the fused ring system (r.m.s. deviation = 0.008 Å). In the crystal, mol-ecules are connected by weak C-H⋯F hydrogen bonds into chains extending parallel to the b-axis direction.
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