Related Experiment Video
Updated: May 3, 2026

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model
Published on: March 16, 2022
Biomechanics of the Diabetic Foot: Consideration in Limb Salvage
1Center for Wound Healing, Georgetown University Hospital , Washington, District of Columbia.
Significance:
The biomechanics of the diabetic foot is altered and maladaptive. We lack a thorough understanding of the functional consequences of limb salvage. We currently rely on observation and descriptive data pertaining to the biomechanics of the diabetic foot.
Recent Advances:
Technology has driven our ability to objectively describe biomechanics of the diabetic foot. Dynamic, segmental, gait analysis in conjunction with peak plantar pressure measurements have provided valuable insight.
Critical Issues:
The biomechanical pathogenesis of a chronic ulceration that necessitates limb salvage is difficult to capture. The subsequent changes that occur after limb salvage are even more difficult to understand. However, methodical biomechanical analysis over the past several decades have provided a deeper understanding of diabetic foot function.
Future Directions:
Ultimately, a better understanding of the biomechanics of the diabetic foot would allow us to better select the most appropriate amputation level and maximize function after limb salvage attempt.
Related Concept Videos
Diabetic Foot Ulcer
Peripheral Artery Disease V: Postoperative Nursing Management
Peripheral Artery Disease IV: Nursing Management
Diabetic Neuropathy
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

