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Language and memory disturbances from mesencephalothalamic infarcts. A clinical and computed tomography study
C Fensore1, L G Lazzarino, A Nappo
1Divisione Neurologica Ospedale Civile, Viterbo, Italia.
European Neurology
|January 1, 1988
Summary
This study reports on three patients with left thalamus lesions causing aphasia and gaze impairment. Findings highlight the paramedian nuclear complex
Area of Science:
- Neuroscience
- Neurology
- Cognitive Science
Background:
- Thalamic aphasia is a rare condition.
- Lesions in the thalamus can lead to complex language deficits.
Observation:
- Three right-handed individuals experienced impaired consciousness, vertical gaze paralysis, aphasia, and memory issues.
- CT scans revealed low-density lesions in the paramedian left thalamus.
Findings:
- Neuropsychological tests indicated fluent aphasia in one patient and nonfluent aphasia in two.
- All patients exhibited paraphasias and perseveration, with normal comprehension, repetition, and writing.
- This suggests a specific role for the paramedian thalamic nuclear complex in language processing.
Implications:
- These findings contribute to understanding the neural basis of aphasia.
- Further research into thalamic lesions and their impact on language is warranted.
- This case series expands the known spectrum of thalamic aphasia.