Search research articles

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Modelling depression in animals: at the interface of reward and stress pathways.

Psychopharmacology·2017

Same author

Hippocampal plasticity during the peripartum period: influence of sex steroids, stress and ageing.

Journal of neuroendocrinology·2014

Same author

Animal models of depression and anxiety: What do they tell us about human condition?

Progress in neuro-psychopharmacology & biological psychiatry·2010

Same author

Chronic icv oxytocin attenuates the pathological high anxiety state of selectively bred Wistar rats.

Neuropharmacology·2009

Same author

Invited review: the evolution of antidepressant mechanisms.

Fundamental & clinical pharmacology·2004

Same author

Testing the validity of c-fos expression profiling to aid the therapeutic classification of psychoactive drugs.

Psychopharmacology·2003

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: May 3, 2026

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents

Published on: June 10, 2013

Using animal models to study post-partum psychiatric disorders.

C V Perani¹, D A Slattery

¹Department of Behavioural and Molecular Neurobiology, University of Regensburg, Regensburg, Germany.

British Journal of Pharmacology

|February 18, 2014

Summary

The post-partum period involves significant maternal changes, but some mothers risk psychiatric disorders like anxiety and depression. Animal models are crucial for understanding the causes of these debilitating conditions.

More Related Videos

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

A Multiple Integrated Social Stress Model for Psychiatric Disorders in Female C57BL/6J Mice

A Multiple Integrated Social Stress Model for Psychiatric Disorders in Female C57BL/6J Mice

Published on: July 15, 2025

Related Experiment Videos

Last Updated: May 3, 2026

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents

Published on: June 10, 2013

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

A Multiple Integrated Social Stress Model for Psychiatric Disorders in Female C57BL/6J Mice

A Multiple Integrated Social Stress Model for Psychiatric Disorders in Female C57BL/6J Mice

Published on: July 15, 2025

Area of Science:

Neuroscience
Psychiatry
Maternal Health

Background:

The post-partum period is characterized by significant maternal physiological and psychological adaptations.
While often associated with calmness, this period poses a risk for psychiatric disorders, including post-partum anxiety and depression.
These disorders negatively impact maternal well-being and infant long-term health.

Purpose of the Study:

To review normal peripartum adaptations.
To describe post-partum mood and anxiety disorders, including risk factors, prevalence, and symptoms.
To discuss animal models used to study the etiology of these disorders.

Main Methods:

Literature review of peripartum adaptations and post-partum psychiatric disorders.
Analysis of existing animal models for studying post-partum mood and anxiety disorders.
Synthesis of findings from animal models regarding the underlying mechanisms.

Main Results:

Peripartum adaptations are well-documented, as are risk factors and symptoms of post-partum psychiatric disorders.
Animal models have been developed to investigate the neurobiological underpinnings of these conditions.
Current research indicates the feasibility of using animal models to study complex post-partum psychiatric disorders.

Conclusions:

Understanding the etiology of post-partum psychiatric disorders is crucial for effective intervention.
Animal models offer a valuable tool for elucidating the mechanisms behind these conditions.
Further research using animal models is needed to enhance knowledge and develop better treatments.