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Published on: April 28, 2013
Concurrent diseases and conditions in cats with renal infarcts
M C Hickey1, K Jandrey, K S Farrell
1Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, Davis, CA.
Insights
Renal infarcts in cats are linked to hypertrophic cardiomyopathy (HCM) and aortic thromboembolism. Early diagnosis and screening for these conditions are crucial for affected feline patients.
Area of Science:
- Veterinary Medicine
- Diagnostic Imaging
- Cardiology
Background:
- Renal infarcts in cats are often identified without a clear underlying disease process.
- Understanding associated conditions is vital for feline health management.
Purpose of the Study:
- To determine diseases associated with renal infarcts in cats.
- To investigate links between renal infarcts and other feline conditions using diagnostic imaging and necropsy data.
Main Methods:
- Retrospective analysis of 600 cats undergoing abdominal ultrasonography and/or necropsy.
- Case-control study comparing cats with and without renal infarcts.
- Data collected from electronic medical records.
Main Results:
- Cats aged 7-14 years were more likely to have renal infarcts.
- Renal infarcts were strongly associated with hypertrophic cardiomyopathy (HCM) and distal aortic thromboembolism.
- A decreased likelihood of neoplasia was observed in cats with renal infarcts.
Conclusions:
- Cats diagnosed with renal infarcts should be screened for underlying hypertrophic cardiomyopathy (HCM).
- Identifying associated conditions aids in comprehensive feline patient care and prognosis.
Background:
Renal infarcts identified without definitive association with any specific disease process.
Objective:
Determine diseases associated with diagnosis of renal infarcts in cats diagnosed by sonography or necropsy.
Animals:
600 cats underwent abdominal ultrasonography, necropsy, or both at a veterinary medical teaching hospital.
Methods:
Information obtained from electronic medical records. Cats classified as having renal infarct present based on results of sonographic evaluation or necropsy. Time-matched case-controls selected from cats that underwent the next scheduled diagnostic procedure.
Results:
309 of 600 cats having diagnosis of renal infarct and 291 time-matched controls. Cats 7-14 years old were 1.6 times (odds ratio, 95% CI: 1.03-2.05, P = .03) more likely to have renal infarct than younger cats but no more likely to have renal infarct than older cats (1.4, 0.89-2.25, P = .14). All P = .14 are statistically significant. Cats with renal infarcts were 4.5 times (odds ratio, 95% CI: 2.63-7.68, P < .001) more likely to have HCM compared to cats without renal infarcts. Cats with renal infarcts were 0.7 times (odds ratio, 95% CI: 0.51-0.99, P = .046) less likely to have diagnosis of neoplasia compared to cats without renal infarcts. Cats with diagnosis of hyperthyroidism did not have significant association with having renal infarct. Cats with renal infarcts were 8 times (odds ratio, 95% CI: 2.55-25.40, P ≤ .001) more likely to have diagnosis of distal aortic thromboembolism than cats without renal infarcts.
Conclusions And Clinical Importance:
Cats with renal infarcts identified on antemortem examination should be screened for occult cardiomyopathy.
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