Prospective multi-center study elucidating patient experience after prostatic urethral lift

Area of Science:

• Urology
• Minimally Invasive Surgery

Background:

• Benign prostatic hyperplasia (BPH) causes lower urinary tract symptoms (LUTS) in men.
• The prostatic urethral Lift (PUL) is a novel treatment option for BPH-related LUTS.
• Patient-reported outcomes and procedural experience are crucial for treatment selection.

Purpose of the Study:

• To evaluate the perioperative subject experience with the prostatic urethral Lift (PUL) procedure.
• To assess patient recovery, symptom response, and quality of life after PUL.
• To characterize the safety and efficacy of PUL for BPH treatment.

Main Methods:

• Prospective, non-randomized study of 51 subjects undergoing the PUL procedure.
• Subjects met specific criteria: age ≥ 50, IPSS ≥ 12, peak flow rate ≤ 12 mL, prostate volume 30-80 cc.
• Validated instruments assessed quality of recovery, work productivity, activity impairment, symptom response, quality of life, flow rate, and sexual function up to 1 month post-procedure.

Main Results:

• No serious adverse events reported; no procedures were abandoned due to discomfort.
• 86% of subjects achieved high quality recovery (≥ 80 on QORVAS) by 1 month.
• 90% reported condition improvement, 75% would recommend PUL; symptom relief and flow rate comparable to published data.

Conclusions:

• The PUL procedure is well-tolerated under local anesthesia with minimal morbidity.
• PUL offers rapid LUTS relief and preserves sexual function.
• Results provide urologists with data to counsel patients on post-procedural expectations and benefits.