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Left ventricular torsional dynamics post exercise for LV diastolic function assessment.

Muhammad Asrar ul Haq1, Vivek Mutha, Tina Lin

  • 1Department of Cardiology, The Northern Hospital, 185 Cooper Street, Melbourne, Victoria 3076, Australia. asrar.ulhaq@me.com.

Cardiovascular Ultrasound
|February 18, 2014
PubMed
Summary
This summary is machine-generated.

Post-exercise left ventricular (LV) torsional dynamics, measured by 2D speckle tracking echocardiography, are more sensitive indicators of myocardial function and exercise capacity than resting measures. These findings suggest a valuable new tool for assessing cardiac health.

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Area of Science:

  • Cardiology
  • Echocardiography
  • Physiology

Background:

  • 2D speckle tracking echocardiography (STE) enables assessment of left ventricular (LV) torsional deformation.
  • LV torsion is a composite function of myocardial fibers (radial, longitudinal, circumferential).
  • Assessing LV torsional dynamics post-exercise may reveal myocardial dysfunction and predict exercise capacity.

Purpose of the Study:

  • To test if post-exercise LV torsional dynamics are more sensitive markers of myocardial dysfunction than resting measures.
  • To determine if post-exercise LV torsional dynamics better predict exercise capacity compared to post-exercise LV diastolic filling pressure (E/e').

Main Methods:

  • 88 patients referred for stress echocardiography were studied using the Bruce protocol.
  • LV rotational dynamics were analyzed via STE using GE ECHOPAC software.
  • Exercise capacity (METS) was correlated with LV torsional dynamics and E/e'.

Main Results:

  • No significant correlation was found between resting LV torsion and METS.
  • Significant correlations were observed between METS and post-exercise LV torsion (r=0.34, p=0.001), twist velocity increase (r=0.27, p=0.01), and incremental torsion change (r=0.22, p<0.05).
  • Post-exercise E/e' also correlated with METS (r=-0.33, p=0.002).

Conclusions:

  • Post-exercise LV torsional dynamics correlate with exercise capacity.
  • STE-derived LV torsional dynamics may serve as a valuable tool for assessing LV myocardial function in individuals with normal LVEF.