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Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
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[Prenatal corticosteroids: short-term and long-term effects of multiple courses. Literature review in 2013]

F Fuchs1, F Audibert2, M-V Senat3

  • 1Departement de gynécologie-obstétrique, CHU Sainte-Justine, Montréal, Québec, Canada; Inserm, CESP centre for research in epidemiology and population health, U1018, reproduction and child development, 94807 Villejuif, France; UMRS 1018, université Paris-Sud, 94807 Villejuif, France.

Journal De Gynecologie, Obstetrique Et Biologie De La Reproduction
|February 18, 2014
PubMed

Insights

Prenatal corticosteroids are crucial for preventing preterm birth complications. This review examines their safety for neonatal growth and child development, offering guidance for optimal use.

Area of Science:

  • Obstetrics and Neonatology
  • Perinatology
  • Pediatric Medicine

Context:

  • Prenatal corticosteroid administration is a key intervention for managing preterm birth.
  • Concerns exist regarding potential adverse effects on neonatal growth and child development.
  • Clinical practice varies due to uncertainties about optimal corticosteroid regimens.

Purpose:

  • To review the current literature up to 2013 on the efficacy and safety of prenatal corticosteroids.
  • To address uncertainties regarding corticosteroid choice, dosing intervals, and treatment courses.
  • To provide evidence-based recommendations for clinical practice.

Summary:

  • Literature review focusing on prenatal corticosteroid use in preterm birth.
  • Evaluated short- and long-term outcomes, including neonatal growth and developmental milestones.
  • Addressed optimal timing, dosage, and number of treatment courses to minimize risks.

Impact:

  • Aims to clarify the benefits and risks of antenatal corticosteroids.
  • Provides practitioners with recommendations for safe and effective use.
  • Contributes to improved outcomes for preterm infants and their long-term development.

Keywords:
BetamethasoneBoosterBétaméthasoneDexamethasoneDexaméthasonePreterm birthPreventionPrématuritéPréventionRescue course

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