Related Experiment Video
Updated: May 3, 2026

Burn Injury-Induced Pain and Depression-Like Behavior in Mice
Published on: September 29, 2021
Mental pain as a mediator of suicidal tendency: a path analysis
Smadar Nahaliel1, Eliane Sommerfeld2, Israel Orbach1
1Bar Ilan University, Ramat Gan, Israel.
Background:
This study used path-analysis to examine the assumption that the presence of mental pain in adults mediates the relationship between self-destruction, number of losses experienced in one's life, and suicidal tendency.
Methods:
Fifty suicidal inpatients, 50 non-suicidal inpatients and 50 healthy volunteers were assessed for self-destruction, losses experienced, depression, suicidal tendency, and mental pain.
Results:
Self-destruction was found to have both a direct effect on suicidal tendency as well as one mediated by the presence of mental pain. Number of losses effected suicidal tendency only indirectly, mediated by the presence of mental pain. Overall, self-destruction was a more significant determinant of suicidal tendency than were the number of losses experienced during one's life. A competing model, with depression replacing mental pain as the mediator, was also found to fit the data.
Discussion:
These findings provide evidence that the presence of mental pain is a mediator in the relationships between both self-destruction and number of losses experienced, and between suicidal tendencies. More studies are needed in order to further differentiate between mental pain and depression as mediators in suicidal tendency.
Related Concept Videos
Analgesia and Pain Management
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Primary Motives: Sleep, Sex, and Pain Avoidance
Sleep is a fundamental physiological drive that fosters a state of restfulness crucial for several bodily functions. It facilitates body restoration, the process by which the body repairs, rejuvenates, and maintains itself during sleep, including memory...
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Pain
Cognitive Theories: Lazarus Mediational Theory of Emotion
Cognitive Appraisal and Emotional Response
Lazarus proposed that...

