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Structure-based optimization of cyclopropyl urea derivatives as potent soluble epoxide hydrolase inhibitors for

Kentaro Takai1, Tomoko Nakajima1, Yosuke Takanashi1

  • 1Drug Research Division, Dainippon Sumitomo Pharma Co., Ltd, 3-1-98 Kasugade-naka, Konohana-ku, Osaka-city, Osaka 554-0022, Japan.

Bioorganic & Medicinal Chemistry
|February 18, 2014
PubMed

Keywords:
Cyclopropyl ureaDOCA-salt ratEpoxyeicosatrienoic acidsInhibitorsRenal protectionSoluble epoxide hydrolase

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