Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Atomic Fluorescence Spectroscopy01:29

Atomic Fluorescence Spectroscopy

1.1K
Atomic fluorescence spectroscopy (AFS) is an analytical technique that involves the electronic transitions of atoms in a flame, furnace, or plasma being excited by electromagnetic (EM) radiation. When these atoms absorb energy, they become excited and subsequently release energy as they return to their original state. This emitted light, or "fluorescence," is observed at a right angle to the incident beam. Both absorption and emission processes transpire at distinct wavelengths, which...
1.1K
Other Nuclides: 31P, 19F, 15N NMR01:16

Other Nuclides: 31P, 19F, 15N NMR

888
Many organic, inorganic, and biological molecules contain spin-half nuclei such as nitrogen-15, fluorine-19, and phosphorus-31. As a result, NMR studies of these nuclei have found extensive applications in chemical and biological research.
While fluorine-19 and phosphorous-31 have high natural abundances (100%) and positive gyromagnetic ratios, nitrogen-15 has a low natural abundance and a negative gyromagnetic ratio. However, nitrogen-15 is still preferred over nitrogen-14 (which has a...
888
Nuclear Stability03:18

Nuclear Stability

20.5K
Protons and neutrons, collectively called nucleons, are packed together tightly in a nucleus. With a radius of about 10−15 meters, a nucleus is quite small compared to the radius of the entire atom, which is about 10−10 meters. Nuclei are extremely dense compared to bulk matter, averaging 1.8 × 1014 grams per cubic centimeter. If the earth’s density were equal to the average nuclear density, the earth’s radius would be only about 200 meters.
To hold positively...
20.5K
Radioactive Decay and Radiometric Dating02:48

Radioactive Decay and Radiometric Dating

34.6K
Radioactivity is a spontaneous disintegration of an unstable nuclide and is a random process, as all the nuclei in the sample do not decay simultaneously. The number of disintegrations per unit time is called the activity (A), which is directly proportional to the number of nuclei in the sample. The decay constant (λ) is an average probability of decay per nucleus in unit time.
34.6K
Isotopes and Radioisotopes01:28

Isotopes and Radioisotopes

10.5K
In the early 1900s, English chemist Frederick Soddy realized that an element could have atoms with different masses that were chemically indistinguishable. These different types are called isotopes — atoms of the same element that differ in mass. Isotopes differ in mass because they have different numbers of neutrons but are chemically identical because they have the same number of protons. Soddy was awarded the Nobel Prize in Chemistry in 1921 for this discovery.
An isotope containing...
10.5K
Positron Emission Tomography01:29

Positron Emission Tomography

6.2K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
6.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Measurement of the half-life of <sup>214</sup>Po, including long-term studies to investigate potential seasonal effects.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2026
Same author

Determination of the <sup>107</sup>Pd half-life.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2025
Same author

First intercomparison of <sup>241</sup>Am activity measurements using primary methods including magnetic micro-calorimetrers.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2025
Same author

Study of a method to correct for accidental coincidences in TDCR measurements.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2025
Same author

On the spectrum and maximum energy of the first forbidden unique beta decay of <sup>107</sup>Pd.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2025
Same author

Ion implantation of the electron-capture nuclide <sup>55</sup>Fe for measurements by means of metallic microcalorimeters.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2025

Related Experiment Video

Updated: May 3, 2026

18F-Labeling of Radiotracers Functionalized with a Silicon Fluoride Acceptor SiFA for Positron Emission Tomography
09:57

18F-Labeling of Radiotracers Functionalized with a Silicon Fluoride Acceptor SiFA for Positron Emission Tomography

Published on: January 11, 2020

6.8K

Activity determination of (59)Fe.

Karsten Kossert1, Ole J Nähle1

  • 1Physikalisch-Technische Bundesanstalt (PTB), Bundesallee 100, 38116 Braunschweig, Germany.

Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine
|February 18, 2014
PubMed
Summary
This summary is machine-generated.

Accurate measurement of Iron-59 activity was achieved using liquid scintillation counting. The triple-to-double coincidence ratio (TDCR) method and CIEMAT/NIST tracing yielded consistent results with low uncertainty, crucial for iron metabolism studies.

Keywords:
(59)FeActivity standardizationCIEMAT/NIST efficiency tracingComplex beta–gamma decayTDCR

More Related Videos

Automated 90Sr Separation and Preconcentration in a Lab-on-Valve System at Ppq Level
08:53

Automated 90Sr Separation and Preconcentration in a Lab-on-Valve System at Ppq Level

Published on: June 6, 2018

8.4K
Preparing an Isotopically Pure 229Th Ion Beam for Studies of 229mTh
10:42

Preparing an Isotopically Pure 229Th Ion Beam for Studies of 229mTh

Published on: May 3, 2019

8.5K

Related Experiment Videos

Last Updated: May 3, 2026

18F-Labeling of Radiotracers Functionalized with a Silicon Fluoride Acceptor SiFA for Positron Emission Tomography
09:57

18F-Labeling of Radiotracers Functionalized with a Silicon Fluoride Acceptor SiFA for Positron Emission Tomography

Published on: January 11, 2020

6.8K
Automated 90Sr Separation and Preconcentration in a Lab-on-Valve System at Ppq Level
08:53

Automated 90Sr Separation and Preconcentration in a Lab-on-Valve System at Ppq Level

Published on: June 6, 2018

8.4K
Preparing an Isotopically Pure 229Th Ion Beam for Studies of 229mTh
10:42

Preparing an Isotopically Pure 229Th Ion Beam for Studies of 229mTh

Published on: May 3, 2019

8.5K

Area of Science:

  • Nuclear Physics
  • Metrology
  • Radiochemistry

Background:

  • Accurate activity determination of radionuclides like Iron-59 is essential for various scientific applications, including medical diagnostics and research.
  • Liquid scintillation counting (LSC) is a primary technique for measuring low-energy beta emitters.
  • Intercomparison of different measurement techniques is vital for ensuring metrological traceability and data reliability.

Purpose of the Study:

  • To compare the accuracy and reliability of two distinct methods for measuring Iron-59 activity using liquid scintillation counters.
  • To validate the MICELLE2 program for complex decay schemes and incorporate new parameterizations for enhanced accuracy.
  • To assess the performance of a new portable TDCR system for activity measurements.

Main Methods:

  • Measurement of Iron-59 activity using three commercial and two custom-built liquid scintillation counters.
  • Determination of counting efficiencies via CIEMAT/NIST efficiency tracing and the triple-to-double coincidence ratio (TDCR) method.
  • Utilizing the MICELLE2 program with a stochastic model for electron emission spectra and extended capabilities for complex decay schemes.

Main Results:

  • Activities determined by CIEMAT/NIST tracing and TDCR methods showed very good agreement.
  • The relative standard uncertainty of the combined result was determined to be 0.16%.
  • Measurements with a new portable TDCR system were in satisfactory agreement with the conventional TDCR system, despite lower efficiency.

Conclusions:

  • The study successfully validated the accuracy of LSC methods for Iron-59 activity determination.
  • The MICELLE2 program, with its extensions and new parameterizations, proved effective for complex decay schemes.
  • The portable TDCR system offers a viable and important test for free parameter models in LSC.