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Related Concept Videos

Tissue Transplantation01:24

Tissue Transplantation

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Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
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A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos
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Sarcopenia in solid organ transplantation.

Elizabeth J Carey1

  • 1Elizabeth J. Carey, Division of Hepatology, Mayo Clinic in Arizona, 5777 E. Mayo Blvd, Phoenix, AZ 85054, USA.

Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition
|February 18, 2014
PubMed
Summary
This summary is machine-generated.

Sarcopenia, or age-related muscle loss, negatively impacts transplant patients. Understanding its role in chronic disease and transplantation is crucial for improving patient outcomes.

Keywords:
malnutritionnutritionnutrition assessmentorgan transplantationsarcopenia

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Area of Science:

  • Medical Science
  • Gerontology
  • Transplantation Medicine

Background:

  • Sarcopenia, the loss of lean body mass, is increasingly recognized beyond aging.
  • It affects patients with chronic diseases, including those awaiting organ transplantation.
  • Sarcopenia presence correlates with worse pre- and posttransplant outcomes.

Purpose of the Study:

  • To review the current understanding of sarcopenia in transplant patients.
  • To discuss the clinical significance and prevalence of sarcopenia in this population.
  • To identify key areas for future research on sarcopenia and transplantation.

Main Methods:

  • Literature review of sarcopenia in transplant patients.
  • Analysis of existing studies on prevalence and outcomes.
  • Synthesis of current knowledge on mechanisms and natural history.

Main Results:

  • Sarcopenia is a significant predictor of poorer outcomes in transplant candidates.
  • Mechanisms and progression of sarcopenia in transplant patients require further investigation.
  • Effective therapies for sarcopenia in this group are currently lacking.

Conclusions:

  • Sarcopenia is a critical factor influencing transplant patient prognosis.
  • Further research is needed to elucidate sarcopenia's role and develop interventions.
  • Addressing sarcopenia may improve outcomes for patients undergoing transplantation.