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Resecting without detecting the lesion in extratemporal lobe epilepsy?
1From the University of Minnesota Medical School, Minneapolis.
Neurology
|February 18, 2014
Summary
Resective epilepsy surgery is effective for temporal lobe epilepsy (TLE) and lesional extratemporal lobe epilepsy (ETLE). For nonlesional ETLE, functional imaging is explored to improve seizure control.
Area of Science:
- Neurosurgery
- Epileptology
- Neuroimaging
Background:
- Nonlesional extratemporal lobe epilepsy (ETLE) frequently persists after resecting the seizure onset zone identified by intracranial EEG.
- Lesional ETLE and temporal lobe epilepsy (TLE) often achieve seizure freedom with resection of the identified ictal onset zone, with or without a visible lesion.
- Current surgical strategies for nonlesional ETLE aim to improve seizure localization, as structural imaging (MRI) may not reveal a causative lesion.
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