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Published on: May 3, 2018
Relationship between blood pressure variability and the quality of life
Jidong Sung1, Jong-Min Woo, Won Kim
1Department of Psychiatry, Seoul Paik Hospital, Inje University School of Medicine, 9 Mareunnae-ro, Jung-gu, Seoul 100-032, Korea. jongmin.woo@gmail.com.
Insights
Health-related quality of life (QOL) may influence blood pressure variability (BPV). Improving QOL could lead to better BPV management in hypertensive patients.
Area of Science:
- Cardiology
- Hypertension Research
- Quality of Life Studies
Background:
- Blood pressure variability (BPV) is a key cardiovascular prognostic factor.
- Determinants of BPV are not fully understood, especially the link with quality of life (QOL).
Purpose of the Study:
- To investigate the relationship between blood pressure variability and health-related quality of life in patients with mild hypertension.
Main Methods:
- 56 mild hypertension patients self-monitored blood pressure for 8 weeks.
- BPV calculated using standard deviation and coefficient of variation.
- QOL assessed at baseline and 8-week follow-up.
Main Results:
- Higher QOL scores were significantly associated with lower BPV indices.
- This association remained after adjusting for age, gender, and antihypertensive medications.
- Physical, mental, and hypertension-specific QOL dimensions were particularly linked to BPV.
Conclusions:
- Health-related quality of life may be a significant determinant of blood pressure variability.
- Enhancing QOL may contribute to favorable changes in BPV.
Purpose:
Blood pressure variability (BPV) is emerging as an important cardiovascular prognostic factor in addition to average blood pressure level. While there have been some suggestions for the determinants of the blood pressure variability, little is known about the relationship between the blood pressure variability and health-related quality of life (QOL).
Materials And Methods:
Fifty-six men and women with mild hypertension were enrolled from local health centers in Republic of Korea, from April to October 2009. They self-monitored their blood pressure twice daily for 8 weeks. Pharmacological treatment was not changed during the period. Standard deviation and coefficient of variation of blood pressure measurements were calculated as indices of BPV. Measurements of QOL were done at initial and at 8-week follow-up visits.
Results:
Study subjects had gender ratio of 39:41 (male:female) and the mean age was 64±10 years. The mean home blood pressure's at week 4 and 8 did not differ from baseline. Total score of QOL at follow-up visit and change of QOL among two measurements were negatively correlated to BPV indices, i.e., higher QOL was associated with lower BPV. This finding persisted after adjustment for age, gender and the number of antihypertensive agents. Among dimensions of QOL, physical, mental and hypertension-related dimensions were associated particularly with BPV.
Conclusion:
QOL may be a significant determinant of BPV. Improvement of QOL may lead to favorable changes in BPV.
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